Human ALMS1 activation kit by CRISPRa

CAT#: GA105330

ALMS1 CRISPRa kit - CRISPR gene activation of human ALMS1 centrosome and basal body associated protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALMS1
• Locus ID: 7840
• Kit Components:

  GA105330G1, ALMS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105330G2, ALMS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105330G3, ALMS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015120
• Synonyms: ALSS
• Summary: This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]