Human Semaphorin 3B (SEMA3B) activation kit by CRISPRa

CAT#: GA105343

SEMA3B CRISPRa kit - CRISPR gene activation of human semaphorin 3B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEMA3B
• Locus ID: 7869
• Kit Components:

  GA105343G1, SEMA3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA105343G2, SEMA3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA105343G3, SEMA3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001005914, NM_001290060, NM_001290061, NM_001290062, NM_001290063, NM_004636, NR_110697
• Synonyms: LUCA-1; SemA; SEMA5; SEMAA; semaV
• Summary: The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]