Human SLBP activation kit by CRISPRa

CAT#: GA105349

SLBP CRISPRa kit - CRISPR gene activation of human stem-loop binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLBP
• Locus ID: 7884
• Kit Components:

  GA105349G1, SLBP gRNA vector 1 in pCas-Guide-CRISPRa

  GA105349G2, SLBP gRNA vector 2 in pCas-Guide-CRISPRa

  GA105349G3, SLBP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306074, NM_001306075, NM_006527
• Synonyms: HBP
• Summary: This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq, Jul 2008]