Human PRRC2A activation kit by CRISPRa

CAT#: GA105354

PRRC2A CRISPRa kit - CRISPR gene activation of human proline rich coiled-coil 2A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRRC2A
• Locus ID: 7916
• Kit Components:

  GA105354G1, PRRC2A gRNA vector 1 in pCas-Guide-CRISPRa

  GA105354G2, PRRC2A gRNA vector 2 in pCas-Guide-CRISPRa

  GA105354G3, PRRC2A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004638, NM_080686
• Synonyms: BAT2; D6S51; D6S51E; G2
• Summary: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]