Human PAFAH (PLA2G7) activation kit by CRISPRa

CAT#: GA105365

PLA2G7 CRISPRa kit - CRISPR gene activation of human phospholipase A2 group VII

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLA2G7
• Locus ID: 7941
• Kit Components:

  GA105365G1, PLA2G7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105365G2, PLA2G7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105365G3, PLA2G7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168357, NM_005084
• Synonyms: LDL-PLA2; LP-PLA2; PAFAD; PAFAH
• Summary: The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2009]