Human NCOA4 activation kit by CRISPRa

CAT#: GA105390

NCOA4 CRISPRa kit - CRISPR gene activation of human nuclear receptor coactivator 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NCOA4
• Locus ID: 8031
• Kit Components:

  GA105390G1, NCOA4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105390G2, NCOA4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105390G3, NCOA4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145260, NM_001145261, NM_001145262, NM_001145263, NM_005437
• Synonyms: ARA70; ELE1; PTC3; RFG
• Summary: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009]