Human Adracalin (AAAS) activation kit by CRISPRa

CAT#: GA105406

AAAS CRISPRa kit - CRISPR gene activation of human aladin WD repeat nucleoporin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AAAS
• Locus ID: 8086
• Kit Components:

  GA105406G1, AAAS gRNA vector 1 in pCas-Guide-CRISPRa

  GA105406G2, AAAS gRNA vector 2 in pCas-Guide-CRISPRa

  GA105406G3, AAAS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173466, NM_015665
• Synonyms: AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003
• Summary: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]