Human Symplekin (SYMPK) activation kit by CRISPRa

CAT#: GA105432

SYMPK CRISPRa kit - CRISPR gene activation of human symplekin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYMPK
• Locus ID: 8189
• Kit Components:

  GA105432G1, SYMPK gRNA vector 1 in pCas-Guide-CRISPRa

  GA105432G2, SYMPK gRNA vector 2 in pCas-Guide-CRISPRa

  GA105432G3, SYMPK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004819
• Synonyms: SPK; SYM
• Summary: This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]