Human DGCR6 activation kit by CRISPRa

CAT#: GA105442

DGCR6 CRISPRa kit - CRISPR gene activation of human DiGeorge syndrome critical region gene 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DGCR6
• Locus ID: 8214
• Kit Components:

  GA105442G1, DGCR6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105442G2, DGCR6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105442G3, DGCR6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005675
• Synonyms: DiGeorge syndrome critical region gene 6; DiGeorge syndrome critical region protein 6
• Summary: DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. [provided by RefSeq, Nov 2008]