Human COLQ activation kit by CRISPRa

CAT#: GA105470

COLQ CRISPRa kit - CRISPR gene activation of human collagen like tail subunit of asymmetric acetylcholinesterase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COLQ
• Locus ID: 8292
• Kit Components:

  GA105470G1, COLQ gRNA vector 1 in pCas-Guide-CRISPRa

  GA105470G2, COLQ gRNA vector 2 in pCas-Guide-CRISPRa

  GA105470G3, COLQ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005677, NM_080538, NM_080539, NM_080540, NM_080541, NM_080542, NM_080543, NM_080544
• Synonyms: EAD
• Summary: This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]