Human DOC2B activation kit by CRISPRa

CAT#: GA105579

DOC2B CRISPRa kit - CRISPR gene activation of human double C2 domain beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DOC2B
• Locus ID: 8447
• Kit Components:

  GA105579G1, DOC2B gRNA vector 1 in pCas-Guide-CRISPRa

  GA105579G2, DOC2B gRNA vector 2 in pCas-Guide-CRISPRa

  GA105579G3, DOC2B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003585
• Synonyms: DOC2BL
• Summary: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]