Human SNF2H (SMARCA5) activation kit by CRISPRa

CAT#: GA105595

SMARCA5 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMARCA5
• Locus ID: 8467
• Kit Components:

  GA105595G1, SMARCA5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105595G2, SMARCA5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105595G3, SMARCA5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003601
• Synonyms: hISWI; hSNF2H; ISWI; SNF2H; WCRF135
• Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]