Human SCARF1 activation kit by CRISPRa

CAT#: GA105688

SCARF1 CRISPRa kit - CRISPR gene activation of human scavenger receptor class F member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCARF1
• Locus ID: 8578
• Kit Components:

  GA105688G1, SCARF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105688G2, SCARF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105688G3, SCARF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003693, NM_145349, NM_145350, NM_145351, NM_145352, NR_028075, NR_028076, NR_102409
• Synonyms: SREC; SREC-I; SREC1
• Summary: The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]