Human PPAP2A (PLPP1) activation kit by CRISPRa

CAT#: GA105700

PLPP1 CRISPRa kit - CRISPR gene activation of human phospholipid phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLPP1
• Locus ID: 8611
• Kit Components:

  GA105700G1, PLPP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105700G2, PLPP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105700G3, PLPP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003711, NM_176895, NR_103485
• Synonyms: LLP1a; LPP1; PAP-2a; PAP2; PPAP2A
• Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]