Human MARCO activation kit by CRISPRa

CAT#: GA105761

MARCO CRISPRa kit - CRISPR gene activation of human macrophage receptor with collagenous structure

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MARCO
• Locus ID: 8685
• Kit Components:

  GA105761G1, MARCO gRNA vector 1 in pCas-Guide-CRISPRa

  GA105761G2, MARCO gRNA vector 2 in pCas-Guide-CRISPRa

  GA105761G3, MARCO gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006770
• Synonyms: SCARA2
• Summary: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]