Human RGS11 activation kit by CRISPRa

CAT#: GA105833

RGS11 CRISPRa kit - CRISPR gene activation of human regulator of G protein signaling 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RGS11
• Locus ID: 8786
• Kit Components:

  GA105833G1, RGS11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105833G2, RGS11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105833G3, RGS11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286485, NM_001286486, NM_003834, NM_183337
• Synonyms: RS11
• Summary: The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]