Human NRP2 activation kit by CRISPRa

CAT#: GA105871

NRP2 CRISPRa kit - CRISPR gene activation of human neuropilin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NRP2
• Locus ID: 8828
• Kit Components:

  GA105871G1, NRP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105871G2, NRP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105871G3, NRP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003872, NM_018534, NM_201264, NM_201266, NM_201267, NM_201279
• Synonyms: NP2; NPN2; PRO2714; VEGF165R2
• Summary: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]