Human PER3 activation kit by CRISPRa
CAT#: GA105900
PER3 CRISPRa kit - CRISPR gene activation of human period circadian regulator 3
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | PER3 |
Locus ID | 8863 |
Kit Components | GA105900G1, PER3 gRNA vector 1 in pCas-Guide-CRISPRa GA105900G2, PER3 gRNA vector 2 in pCas-Guide-CRISPRa GA105900G3, PER3 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001289861, NM_001289862, NM_001289863, NM_001289864, NM_016831 |
Synonyms | FASPS3; GIG13 |
Summary | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN417739 | PER3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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