Human MTMR2 activation kit by CRISPRa

CAT#: GA105929

MTMR2 CRISPRa kit - CRISPR gene activation of human myotubularin related protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MTMR2
• Locus ID: 8898
• Kit Components:

  GA105929G1, MTMR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105929G2, MTMR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105929G3, MTMR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243571, NM_016156, NM_201278, NM_201281, NR_023354, NR_023355, NR_023356
• Synonyms: CMT4B; CMT4B1
• Summary: This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]