Human Glycogenin 2 (GYG2) activation kit by CRISPRa

CAT#: GA105936

GYG2 CRISPRa kit - CRISPR gene activation of human glycogenin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GYG2
• Locus ID: 8908
• Kit Components:

  GA105936G1, GYG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105936G2, GYG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105936G3, GYG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079855, NM_001184702, NM_001184703, NM_001184704, NM_003918
• Synonyms: GN-2; GN2
• Summary: This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2010]