Human HERC3 activation kit by CRISPRa

CAT#: GA105944

HERC3 CRISPRa kit - CRISPR gene activation of human HECT and RLD domain containing E3 ubiquitin protein ligase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HERC3
• Locus ID: 8916
• Kit Components:

  GA105944G1, HERC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105944G2, HERC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105944G3, HERC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271602, NM_001318505, NM_014606
• Summary: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]