Human ANGPTL1 activation kit by CRISPRa

CAT#: GA106031

ANGPTL1 CRISPRa kit - CRISPR gene activation of human angiopoietin like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANGPTL1
• Locus ID: 9068
• Kit Components:

  GA106031G1, ANGPTL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106031G2, ANGPTL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106031G3, ANGPTL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004673
• Synonyms: ANG3; ANGPT3; AngY; ARP1; dJ595C2.2; UNQ162
• Summary: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]