Human PIGQ activation kit by CRISPRa

CAT#: GA106050

PIGQ CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class Q

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGQ
• Locus ID: 9091
• Kit Components:

  GA106050G1, PIGQ gRNA vector 1 in pCas-Guide-CRISPRa

  GA106050G2, PIGQ gRNA vector 2 in pCas-Guide-CRISPRa

  GA106050G3, PIGQ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004204, NM_148920
• Synonyms: c407A10.1; GPI1
• Summary: This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]