Human GEF H1 (ARHGEF2) activation kit by CRISPRa

CAT#: GA106120

ARHGEF2 CRISPRa kit - CRISPR gene activation of human Rho/Rac guanine nucleotide exchange factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARHGEF2
• Locus ID: 9181
• Kit Components:

  GA106120G1, ARHGEF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106120G2, ARHGEF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106120G3, ARHGEF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001162383, NM_001162384, NM_004723, NM_001350110, NM_001350111, NM_001350112
• Synonyms: GEF; GEF-H1; GEFH1; LFP40; P40
• Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2009]