Human MSC activation kit by CRISPRa

CAT#: GA106163

MSC CRISPRa kit - CRISPR gene activation of human musculin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSC
• Locus ID: 9242
• Kit Components:

  GA106163G1, MSC gRNA vector 1 in pCas-Guide-CRISPRa

  GA106163G2, MSC gRNA vector 2 in pCas-Guide-CRISPRa

  GA106163G3, MSC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005098
• Synonyms: ABF-1; ABF1; bHLHa22; MYOR
• Summary: The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]