Human UBE2L6 activation kit by CRISPRa

CAT#: GA106166

UBE2L6 CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 L6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBE2L6
• Locus ID: 9246
• Kit Components:

  GA106166G1, UBE2L6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106166G2, UBE2L6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106166G3, UBE2L6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004223, NM_198183
• Synonyms: RIG-B; UBCH8
• Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]