Human TMPRSS11D activation kit by CRISPRa

CAT#: GA106278

TMPRSS11D CRISPRa kit - CRISPR gene activation of human transmembrane serine protease 11D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMPRSS11D
• Locus ID: 9407
• Kit Components:

  GA106278G1, TMPRSS11D gRNA vector 1 in pCas-Guide-CRISPRa

  GA106278G2, TMPRSS11D gRNA vector 2 in pCas-Guide-CRISPRa

  GA106278G3, TMPRSS11D gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004262
• Synonyms: HAT
• Summary: This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]