Human AKAP7 activation kit by CRISPRa

CAT#: GA106322

AKAP7 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKAP7
• Locus ID: 9465
• Kit Components:

  GA106322G1, AKAP7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106322G2, AKAP7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106322G3, AKAP7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004842, NM_016377, NM_138633
• Synonyms: AKAP15; AKAP18
• Summary: This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2011]