Human GAL3ST1 activation kit by CRISPRa

CAT#: GA106360

GAL3ST1 CRISPRa kit - CRISPR gene activation of human galactose-3-O-sulfotransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GAL3ST1
• Locus ID: 9514
• Kit Components:

  GA106360G1, GAL3ST1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106360G2, GAL3ST1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106360G3, GAL3ST1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318103, NM_001318104, NM_001318105, NM_001318106, NM_001318107, NM_001318108, NM_001318109, NM_001318110, NM_001318111, NM_001318112, NM_001318113, NM_001318114, NM_001318115, NM_001318116, NM_004861
• Synonyms: CST
• Summary: Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. This gene encodes galactosylceramide sulfotransferase, which catalyzes the sulfation of membrane glycolipids including the final step in the synthesis of sulfatide, a major lipid component of the myelin sheath. This gene exhibits elevated expression in ovarian epithelial carcinoma and the encoded enzyme exhibits elevated activity in renal cell carcinoma. Mutations in this gene may be associated with reduced insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]