Human AATK activation kit by CRISPRa

CAT#: GA106445

AATK CRISPRa kit - CRISPR gene activation of human apoptosis associated tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AATK
• Locus ID: 9625
• Kit Components:

  GA106445G1, AATK gRNA vector 1 in pCas-Guide-CRISPRa

  GA106445G2, AATK gRNA vector 2 in pCas-Guide-CRISPRa

  GA106445G3, AATK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080395, NM_004920
• Synonyms: AATYK; AATYK1; LMR1; LMTK1; p35BP; PPP1R77
• Summary: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]