Human GCAP3 (GUCA1C) activation kit by CRISPRa

CAT#: GA106446

GUCA1C CRISPRa kit - CRISPR gene activation of human guanylate cyclase activator 1C


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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol GUCA1C
Locus ID 9626
Kit Components

GA106446G1, GUCA1C gRNA vector 1 in pCas-Guide-CRISPRa

GA106446G2, GUCA1C gRNA vector 2 in pCas-Guide-CRISPRa

GA106446G3, GUCA1C gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_005459, NM_001363884
Synonyms GCAP3
Summary Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure. [UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.