Human Malectin (MLEC) activation kit by CRISPRa

CAT#: GA106567

MLEC CRISPRa kit - CRISPR gene activation of human malectin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MLEC
• Locus ID: 9761
• Kit Components:

  GA106567G1, MLEC gRNA vector 1 in pCas-Guide-CRISPRa

  GA106567G2, MLEC gRNA vector 2 in pCas-Guide-CRISPRa

  GA106567G3, MLEC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303627, NM_001303628, NM_014730
• Synonyms: KIAA0152
• Summary: This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]