Human BTF (BCLAF1) activation kit by CRISPRa

CAT#: GA106577

BCLAF1 CRISPRa kit - CRISPR gene activation of human BCL2 associated transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BCLAF1
• Locus ID: 9774
• Kit Components:

  GA106577G1, BCLAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106577G2, BCLAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106577G3, BCLAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077440, NM_001077441, NM_001301038, NM_014739, NM_001363659
• Synonyms: bK211L9.1; BTF
• Summary: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]