Human IST1 activation kit by CRISPRa

CAT#: GA106600

IST1 CRISPRa kit - CRISPR gene activation of human IST1 factor associated with ESCRT-III

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IST1
• Locus ID: 9798
• Kit Components:

  GA106600G1, IST1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106600G2, IST1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106600G3, IST1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270975, NM_001270976, NM_001270977, NM_001270978, NM_001270979, NM_014761
• Synonyms: OLC1
• Summary: This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]