Human DNAJC6 activation kit by CRISPRa

CAT#: GA106625

DNAJC6 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member C6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJC6
• Locus ID: 9829
• Kit Components:

  GA106625G1, DNAJC6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106625G2, DNAJC6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106625G3, DNAJC6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256864, NM_001256865, NM_014787
• Synonyms: DJC6; PARK19
• Summary: DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). [supplied by OMIM, Mar 2008]