Human HELZ activation kit by CRISPRa

CAT#: GA106715

HELZ CRISPRa kit - CRISPR gene activation of human helicase with zinc finger

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HELZ
• Locus ID: 9931
• Kit Components:

  GA106715G1, HELZ gRNA vector 1 in pCas-Guide-CRISPRa

  GA106715G2, HELZ gRNA vector 2 in pCas-Guide-CRISPRa

  GA106715G3, HELZ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330447, NM_014877
• Synonyms: DHRC; DRHC; HUMORF5
• Summary: HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]). [supplied by OMIM, Mar 2008]