Human FGFBP1 activation kit by CRISPRa

CAT#: GA106756

FGFBP1 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGFBP1
• Locus ID: 9982
• Kit Components:

  GA106756G1, FGFBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106756G2, FGFBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106756G3, FGFBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005130
• Synonyms: FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17
• Summary: This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]