Human HDAC6 activation kit by CRISPRa

CAT#: GA106781

HDAC6 CRISPRa kit - CRISPR gene activation of human histone deacetylase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HDAC6
• Locus ID: 10013
• Kit Components:

  GA106781G1, HDAC6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106781G2, HDAC6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106781G3, HDAC6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001321225, NM_001321226, NM_001321227, NM_001321228, NM_001321229, NM_001321230, NM_001321231, NM_006044, NR_135591, NR_135592, NR_135593
• Synonyms: CPBHM; HD6; JM21; PPP1R90
• Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]