Human ARPC4 activation kit by CRISPRa

CAT#: GA106843

ARPC4 CRISPRa kit - CRISPR gene activation of human actin related protein 2/3 complex subunit 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARPC4
• Locus ID: 10093
• Kit Components:

  GA106843G1, ARPC4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106843G2, ARPC4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106843G3, ARPC4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024959, NM_001024960, NM_001198780, NM_005718
• Synonyms: ARC20; P20-ARC
• Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]