Human GPR64 (ADGRG2) activation kit by CRISPRa

CAT#: GA106890

ADGRG2 CRISPRa kit - CRISPR gene activation of human adhesion G protein-coupled receptor G2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADGRG2
• Locus ID: 10149
• Kit Components:

  GA106890G1, ADGRG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106890G2, ADGRG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106890G3, ADGRG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079858, NM_001079859, NM_001079860, NM_001184833, NM_001184834, NM_001184835, NM_001184836, NM_001184837, NM_005756
• Synonyms: EDDM6; GPR64; HE6; TM7LN2
• Summary: This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]