Human SLC25A13 activation kit by CRISPRa

CAT#: GA106905

SLC25A13 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A13
• Locus ID: 10165
• Kit Components:

  GA106905G1, SLC25A13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106905G2, SLC25A13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106905G3, SLC25A13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001160210, NM_014251, NR_027662
• Synonyms: ARALAR2; CITRIN; CTLN2
• Summary: This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]