Human DDX39 (DDX39A) activation kit by CRISPRa

CAT#: GA106942

DDX39A CRISPRa kit - CRISPR gene activation of human DExD-box helicase 39A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DDX39A
• Locus ID: 10212
• Kit Components:

  GA106942G1, DDX39A gRNA vector 1 in pCas-Guide-CRISPRa

  GA106942G2, DDX39A gRNA vector 2 in pCas-Guide-CRISPRa

  GA106942G3, DDX39A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204057, NM_005804, NM_138998, NR_038336, NR_046366
• Synonyms: BAT1; BAT1L; DDX39; DDXL; MGC8417; MGC18203; URH49
• Summary: This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]