Human TRIP (TRAIP) activation kit by CRISPRa

CAT#: GA107013

TRAIP CRISPRa kit - CRISPR gene activation of human TRAF interacting protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRAIP
• Locus ID: 10293
• Kit Components:

  GA107013G1, TRAIP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107013G2, TRAIP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107013G3, TRAIP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005879
• Synonyms: RNF206; SCKL9; TRIP
• Summary: This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]