Human ABCA9 activation kit by CRISPRa

CAT#: GA107055

ABCA9 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily A member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCA9
• Locus ID: 10350
• Kit Components:

  GA107055G1, ABCA9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107055G2, ABCA9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107055G3, ABCA9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_080283, NM_172386
• Synonyms: EST640918
• Summary: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]