Human WARS2 activation kit by CRISPRa

CAT#: GA107057

WARS2 CRISPRa kit - CRISPR gene activation of human tryptophanyl tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WARS2
• Locus ID: 10352
• Kit Components:

  GA107057G1, WARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107057G2, WARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107057G3, WARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015836, NM_201263
• Synonyms: TrpRS
• Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]