Human BTN2A2 activation kit by CRISPRa

CAT#: GA107075

BTN2A2 CRISPRa kit - CRISPR gene activation of human butyrophilin subfamily 2 member A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BTN2A2
• Locus ID: 10385
• Kit Components:

  GA107075G1, BTN2A2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107075G2, BTN2A2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107075G3, BTN2A2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001197237, NM_001197238, NM_001197239, NM_001197240, NM_006995, NM_181531
• Synonyms: BT2.2; BTF2; BTN2.2
• Summary: Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]