Human LRRN5 (LRRN2) activation kit by CRISPRa

CAT#: GA107124

LRRN2 CRISPRa kit - CRISPR gene activation of human leucine rich repeat neuronal 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LRRN2
• Locus ID: 10446
• Kit Components:

  GA107124G1, LRRN2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107124G2, LRRN2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107124G3, LRRN2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006338, NM_201630
• Synonyms: FIGLER7; GAC1; LRANK1; LRRN5
• Summary: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]