Human PRMT4 (CARM1) activation kit by CRISPRa

CAT#: GA107172

CARM1 CRISPRa kit - CRISPR gene activation of human coactivator associated arginine methyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CARM1
• Locus ID: 10498
• Kit Components:

  GA107172G1, CARM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107172G2, CARM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107172G3, CARM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_199141, NM_001370088, NM_001370089
• Synonyms: PRMT4
• Summary: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]