Human CIB2 activation kit by CRISPRa

CAT#: GA107184

CIB2 CRISPRa kit - CRISPR gene activation of human calcium and integrin binding family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CIB2
• Locus ID: 10518
• Kit Components:

  GA107184G1, CIB2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107184G2, CIB2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107184G3, CIB2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271888, NM_001271889, NM_001301224, NM_006383, NR_125435
• Synonyms: DFNB48; KIP2; USH1J
• Summary: The protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs), and it is involved in photoreceptor cell maintenance. Mutations in this gene cause deafness, autosomal recessive, 48 (DFNB48), and also Usher syndrome 1J (USH1J). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]