Human AP4B1 activation kit by CRISPRa

CAT#: GA107342

AP4B1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 4 subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AP4B1
• Locus ID: 10717
• Kit Components:

  GA107342G1, AP4B1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107342G2, AP4B1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107342G3, AP4B1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253852, NM_001253853, NM_001308312, NM_006594
• Synonyms: BETA-4; CPSQ5; SPG47
• Summary: This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]